Epidemiological analysis of nifedipine and phenytoin-induced gingival overgrowth in users of the Primary Health Care System
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چکیده
منابع مشابه
Epidemiological analysis of nifedipine and phenytoin-induced gingival overgrowth in users of the Primary Health Care System
Methods: Demographic, pharmacological, and periodontal data were obtained from 100 users of the Brazilian Primary Health Care System in Diamantina, Jequitinhonha Valley, Minas Gerais state, Brazil, who were taking nifedipine and/or phenytoin. Clinical evaluations including gingival overgrowth analysis were carried out by a single calibrated examiner. Bivariate analysis (Chi-square test or Stude...
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Gingival overgrowth is a common adverse effect of therapy with Phenytoin, having important medical and cosmetic implications. Poor periodontal hygiene is an important risk factor for severity of Phenytoin-induced gingival overgrowth (PIGO), which is a time-dependent process. There is complex interplay of altered fibroblast biology, connective tissue turnover, inflammatory processes, and growth ...
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Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosp...
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ژورنال
عنوان ژورنال: Revista Odonto Ciência (Online)
سال: 2010
ISSN: 1980-6523
DOI: 10.1590/s1980-65232010000200007